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作者:林芳 蔡明伟 杜驰 苏先华
目的 探讨中药对结直肠癌术后化疗所致毒副反应的疗效。方法 以我院42例结直肠癌手术后化疗患者为试验组,以同期收治的的40例结直肠癌手术后化疗患者为对照组。对照组给予单纯的化疗,试验组在给予化疗的同时,给予中药治疗,比较2组的化疗不良反应。结果 试验组消化道不良反应的发生率均明显低于对照组,P<0.05,差异具有统计学意义;化疗前,2组血常规WBC的差异没有统计学意义,经过中医辅助治疗后,试验组WBC明显高于对照组,P<0.05,差异具有统计学意义。结论 结直肠癌术后化疗期间给予中药治疗,能有效增强免疫,减轻毒副反应,提高化疗效果。
结直肠癌 化疗 中医
Objective:To investigate the the effeacy of traditional Chinese medicine for postoperative chemotherapy-induced toxicity of colorectal cancer.Methods:42 cases of postoperative colorectal cancer receiving chemotherapy were as the experimental group in our hospital.40 cases of postoperative colorectal cancer receiving chemotherapy were as the control group at the same period.The control group received chemotherapy alone.The experimental group received the chemotherapy and traditional chinese medicine.To compared the adverse reactions of chemotherapy in 2 groups.Results:The incidence rate of gastrointestinal adverse reactions in the experimental group was lower than the control group.The difference was statistically significant,P<0.05.The WBC in blood was not
结直肠恶性肿瘤患者机体免疫功能一般低于正常人,手术切除仅仅是局部控制原发病灶及区域淋巴结,而化疗是巩固疗效、预防肿瘤复发和转移、提高生存率的一个重要方面。但是,化疗导致的胃肠功能紊乱、白细胞下降、肝功能受损及神经毒性等毒副反应,使很多患者不得不终止化疗,大大降低手术疗效[1]。为了降低化疗毒副反应,我们采用中医辨证论治的方法,内服中药治疗结直肠癌术后化疗毒副反应,并与单纯化疗比较,疗效满意,报道如下。
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